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Adacel Vaccination in Lucknow


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Adacel Vaccination

Availability: Service available Location: Vaccination at centre/ Home Vaccination Category: Tdap

Indication and Usage –

  • Adacel is a vaccine indicated for active booster immunization against tetanus, diphtheria and pertussis.
  • Adacel is approved for use in individuals 10 through 64 years of age.


Dosage and Administration –

  • Adacel is administered as a single 0.5 mL intramuscular injection.
  • A first dose of Adacel is administered 5 years or more after the last dose of the Diphtheria and Tetanus Toxoids and Acellular Pertussis (DTaP) series or 5 years or more after a dose of Tetanus and Diphtheria Toxoids Adsorbed (Td).
  • A second dose of Adacel may be administered 8 years or more after the first dose of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (Tdap).


Contraindications –

  • Hypersensitivity
  1. A severe allergic reaction (eg, anaphylaxis) after a previous dose of any tetanus toxoid, diphtheria toxoid or pertussis containing vaccine or any other component of this vaccine is a contraindication to administration of Adacel
  2. Because of uncertainty as to which component of the vaccine may be responsible, none of the components should be 3 administered. Alternatively, such individuals may be referred to an allergist for evaluation if further immunizations are to be considered.
  • Encephalopathy
  1. Encephalopathy (eg, coma, prolonged seizures, or decreased level of consciousness) within 7 days of a previous dose of a pertussis containing vaccine not attributable to another identifiable cause is a contraindication to administration of any pertussis containing vaccine, including Adacel.

Adverse reactions –

  • Immune system disorders

Anaphylactic reaction, hypersensitivity reaction (angioedema, edema, rash, hypotension)

  • Nervous system disorders

Paresthesia, hypoesthesia, Guillain-Barré syndrome, brachial neuritis, facial palsy, convulsion, syncope, myelitis

  • Cardiac disorders


  • Skin and subcutaneous tissue disorders

Pruritus, urticaria

  • Musculoskeletal and connective tissue disorders

Myositis, muscle spasm

  • General disorders and administration site conditions

Large injection site reactions (>50 mm), extensive limb swelling from the injection site beyond one or both joints Injection site bruising, sterile abscess, Arthus hypersensitivity

Drug interactions and other interactions –

  • When Adacel is administered concomitantly with other injectable vaccines or Tetanus Immune Globulin, they should be given with separate syringes and at different injection sites.
  • Adacel should not be mixed with any other vaccine in the same syringe or vial.
  • Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs and corticosteroids (used in greater than physiologic doses), may reduce the immune response to vaccines.




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