HEXASIIL is indicated for the active immunization of infants aged 6 weeks or older against Diphtheria, Tetanus, Pertussis, Hepatitis B, Poliomyelitis, and invasive diseases caused by Haemophilus influenzae type b. This is administered in a 3-dose regimen at 6, 10, and 14 weeks for primary vaccination, with a booster dose recommended at the age of 12-24 months.
The HEXASIIL liquid vaccine vial/PFS should be shaken before use to homogenize the suspension and administered intramuscularly. The recommended injection sites are generally the antero-lateral aspect of the upper thigh in infants and toddlers. It should not be administered via intravascular, intradermal, or subcutaneous injection. A sterile syringe and sterile needle must be used for the injection, and any other injection co-administered with HEXASIIL should be given at a different site.
For primary vaccination, 3 doses of 0.5 ml each should be administered, with an interval of at least four weeks between doses, starting at six weeks of age. In countries where perinatal transmission of hepatitis B virus (HBV) is common, the first dose of Hepatitis B should be given as soon as possible after birth. In this case, HEXASIIL can be used to complete the primary series from 6 weeks of age.
A booster dose of DTP, Hib, and IPV should be given preferably during the second year of life (≥ 6 months after the last primary dose). Booster doses should be given in accordance with official recommendations. Booster doses may be provided to children who have received the primary vaccination of HEXASIIL or any other DTP-containing vaccine and Poliomyelitis Vaccine (OPV and/or IPV).
The composition of each 0.5 ml dose includes:
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